Blood eosinophil and neutrophil counts differentially identify frequent exacerbation in patients with COPD with physician-diagnosed asthma and COPD

摘要

Patients presenting with clinical features of both asthma and COPD are categorized into a specific group called asthma-COPD overlap (ACO). A recent survey reported the prevalence of ACO to be 29.6% (95%CI: 19.3e39.9%) among patients with COPD. 1 ACO is related to frequent exacerbation. 2 However, useful biomarkers for predictingexacerbationinACOpatientsremainunderinvestigation.