PRELIMINARY PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTIMICROBIAL ACTIVITY OF SILVER NANO PARTICLES OF?A. CADAMBA?BARK (AgNPsC)

摘要

In recent times, green biosynthesis of nanoparticles has generated wide interest due to their stability, rapidity, cheaper cost and eco-friendly behaviour.In present study Anthocephalus cadamba bark extract based silver nanoparticles (AgNPsC) are synthesized and size was analyzed by dynamic light scattering (DLS) using Zeta sizer nano (ZS), Malvern, instrument, UK.These nanoparticles were screened for antimicrobial activity against E.coli, B.subtilis, S.aureus and P.aureginosa and compared with antimicrobial activity of silver nitrate and hydro-methanolic bark extract of A.cadamba.Result suggested that AgNPsC exhibit much higher zone of inhibition with respect to AgNO3 and hydro-methanolic A.cadamba bark extract.Among various bacterial strains E.coli and S.aureus were found to be more sensitive against AgNPsC.Thus these AgNPsC can be a good alternative therapeutic approach in future and can be used as an effective antimicrobial material.