VITAMIN D AND DIABETES, PATHOPHYSIOLOGY, DIETARY SIGNIFICANCE?AND RECOMMENDATION

摘要

There are also evidences suggesting that altered calcium and vitamin D homeostasis plays a role in the development of diabetes.Low levels of activated vitamin D are associated with glucose intolerance, diabetes, insulin resistance and metabolic syndrome; all increasing the potential for the development of type 2 diabetes Vitamins can be taken up from the foods like fish and oils but the major source is sunlight.Vitamin D exerts its effects by binding to its nuclear receptor (VDR).VDR are present on pancreatic 尾-cells and vitamin D is essential for normal insulin secretion.Insulin secretion is reduced in animal models with vitamin D deficiency.The Aim of this review is to emphasize the role of Vitamin D for Diabetes and Daily Recommended use for Prevention of advanced risk factors.