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Allergic rhinoconjunctivitis: pathophysiological mechanism and new therapeutic approach

机译:过敏性鼻咽炎:病理生理机制和新的治疗方法

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Allergic rhinoconjunctivitis (AR) is the most common IgE-mediated disease. A type2 immune response is involved in AR pathogenesis. Allergic inflammation is characterized by eosinophilic infiltrate and mediators release. AR treatment is usually based on medication prescription, including antihistamines and intranasal corticosteroids. However, medications may be prescribed for long periods and sometimes may be scarcely effective, thus aggressive strategy should be used. Therefore, complementary medicine is becoming attractive for patients at present. Nutraceuticals represent interesting therapeutic options in clinical practice. In this regard, a new compound has been designed containing Vitamin D3, Perilla extract, and quercetin.
机译:过敏性鼻咽炎(AR)是最常见的IgE介导的疾病。 A型免疫应答参与AR发病机制。过敏性炎症的特征在于嗜酸性渗透液和介质释放。 AR治疗通常基于药物处方,包括抗组胺药和鼻内皮质类固醇。然而,可以长期规定药物,有时可能几乎没有有效,因此应该使用侵略性的策略。因此,互补药对目前的患者变得有吸引力。 Nutraceuticals代表临床实践中有趣的治疗选择。在这方面,设计了一种含有维生素D3,紫苏提取物和槲皮素的新化合物。

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