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首页> 外文期刊>Communications in Mathematical Biology and Neuroscience >Optimal controls analysis of HIV/AIDS transmission model with an aware population
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Optimal controls analysis of HIV/AIDS transmission model with an aware population

机译:感知人口艾滋病毒/艾滋病传输模型的最佳控制分析

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摘要

In this paper, a mathematical model that describes the transmission dynamics of HIV/AIDS with an awareness effect is studied. We analyze the existence and stability of the model equilibriums of HIV/AIDS based on the basic reproduction number. Parameter sensitivity analysis was also conducted to determine the most influential parameters on the spread of this disease. Furthermore, we apply the optimal controls on the HIV model in the form of prevention, campaign, and treatment of Antiretroviral Therapy (ART). The optimal control problems are solved using Pontryagin's Maximum Principle. Numerical simulation results show that the combination of prevention and campaign effort can effectively minimize the number of human populations infected with HIV/AIDS.
机译:在本文中,研究了描述具有意识效果的艾滋病毒/艾滋病传播动态的数学模型。我们根据基本再现数分析艾滋病毒/艾滋病模型平衡的存在和稳定性。还进行了参数敏感性分析,以确定对该疾病传播的最有影响力的参数。此外,我们以防止,运动和抗逆转录病毒治疗(艺术)的形式应用于HIV模型的最佳控制。利用Pontryagin的最大原理解决了最佳控制问题。数值模拟结果表明,预防和竞选工作的结合可以有效地减少艾滋病毒/艾滋病感染的人口数量。

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