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Free-text and Structured Clinical Time Series for Patient Outcome Predictions

机译:患者结果预测的自由文本和结构化临床时间序列

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While there has been considerable progress in building deep learning models based on clinical time series data, overall machine learning (ML) performance remains modest. Typical ML applications struggle to combine various heterogenous sources of Electronic Medical Record (EMR) data, often recorded as a combination of free-text clinical notes and structured EMR data. The goal of this work is to develop an approach for combining such heterogenous EMR sources for time-series based patient outcome predictions. We developed a deep learning framework capable of representing free-text clinical notes in a low dimensional vector space, semantically representing the overall patient medical condition. The free-text based time-series vectors were combined with time-series of vital signs and lab results and used to predict patients at risk of developing a complex and deadly condition: acute respiratory distress syndrome. Results utilizing early data show significant performance improvement and validate the utility of the approach.
机译:虽然基于临床时间序列数据构建深度学习模型,但整体机器学习(ML)性能仍保持适度。典型的ML应用程序努力将各种异质源的电子医疗记录(EMR)数据结合起来,通常记录为自由文本临床笔记和结构化EMR数据的组合。这项工作的目标是开发一种方法,用于组合这种异构EMR源以进行时间序列的基于患者结果预测。我们开发了一个能够在低维矢量空间中代表自由文本临床笔记的深度学习框架,语义代表整体患者的医疗状况。基于自由文本的时间序列载体与时间序列和实验室结果相结合,并用于预测有患有复杂和致命条件的风险的患者:急性呼吸窘迫综合症。结果利用早期数据显示出显着的性能改进并验证了这种方法的效用。

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