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Biomedical Study of Demographics and Clinical Features of Lichen Planopilaris among the Iranian Population

机译:伊朗人口地衣普拉斯人口统计学和临床​​特征的生物医学研究

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Introduction: The demographic of Lichen PlanoPilaris (LPP) among the Iranian population is unknown. The aim of this study is to describe the clinical, demographic, and histopathologic findings of lichen planopilaris in the Iranian population. Method: In this cross-sectional study, all the patients with Lichen planopilaris were referred to the dermatology clinic of Imam Khomeini hospital from 2013 to 2015. Their demographic characteristics, drug histories, onset of disease, and family histories were obtained by written questionnaire. Additionally, this study employed SPSS v.20 as the statistical analysis software. Results: One hundred patients were enrolled in this study. With an average age of 47.11 years, 78% of the patients were female, and 50 of these were housewives. The patients included were often from Tehran with Fars ethnicity. Among these patients, 7 had alopecia areata skin disease, and 10 of them suffered from thyroid disease. Most of the histopathology samples collected from these biopsies revealed degeneration of the basal layer of the follicular structure, perifollicular fibrosis, inflammatory cells, and atrophy of the pilosebaceous structures. Conclusion: Both the age spectrum and the disease distribution of LPP among the Iranian population were very diverse when compared to previous studies.
机译:简介:伊朗人口中的地衣Planopararis(LPP)的人口尚不清楚。本研究的目的是描述伊朗人口地区地衣普拉斯普拉斯的临床,人口和组织病理学发现。方法:在这项横断面研究中,从2013年至2013年开始,所有患有地衣Planopilaris的患者都被提到了IMAM Khomeini医院的皮肤病学诊所。他们的人口特征,药物历史,疾病发病和家族历史是由书面调查问卷获得的。此外,本研究采用SPSS V.20作为统计分析软件。结果:本研究招募了一百款患者。平均年龄为47.11岁,78%的患者是女性,其中50个是家庭主妇。包括的患者往往来自德黑兰,具有远的种族。在这些患者中,7例患有脱脂症状皮肤病,其中10名患有甲状腺疾病的10个。从这些活检收集的大多数组织病理学样本揭示了滤泡结构,纤毛纤维化,炎症细胞和皮质结构萎缩结构的基底层的退化。结论:与以前的研究相比,伊朗人群中LPP的年龄谱和疾病分布都非常多样化。

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