Electrophoretic Deposition and Characterization of Chitosan/Eudragit E 100 Coatings on Titanium Substrate

摘要

Currently, a significant problem is the production of coatings for titanium implants, which will be characterized by mechanical properties comparable to those of a human bone, high corrosion resistance, and low degradation rate in the body fluids. This paper aims to describe the properties of novel chitosan/Eudragit E 100 (chit/EE100) coatings deposited on titanium grade 2 substrate by the electrophoretic technique (EPD). The deposition was carried out for different parameters like the content of EE100, time of deposition, and applied voltage. The microstructure, surface roughness, chemical and phase composition, wettability, mechanical and electrochemical properties, and degradation rate at different pH were examined in comparison to chitosan coating without the addition of Eudragit E 100. The applied deposition parameters significantly influenced the morphology of the coatings. The chit/EE100 coating with the highest homogeneity was obtained for Eudragit content of 0.25 g, at 10 V, and for 1 min. Young’s modulus of this sample (24.77 ± 5.50 GPa) was most comparable to that of human cortical bone. The introduction of Eudragit E 100 into chitosan coatings significantly reduced their degradation rate in artificial saliva at neutral pH while maintaining high sensitivity to pH changes. The chit/EE100 coatings showed a slightly lower corrosion resistance compared to the chitosan coating, however, significantly exceeding the substrate corrosion resistance. All prepared coatings were characterized by hydrophilicity.