Cirrhosis caused by viral and alcoholic hepatitis is an essential cause of portal hypertension (PHT). The incidence of PHT complication is directly proportional to portal venous pressure (PVP), and the clinical research of PVP and its hemodynamic indexes is of great significance for deciding the treatment strategy of PHT. Various techniques are currently being developed to decrease portal pressure but hemodynamic side effects may occur. In this article, the hemodynamic indexes of cirrhotic PHT patients were studied to explore the correlation between the index and PVP and to evaluate the clinical value of Doppler ultrasound in measuring PVP in patients with PHT. This was achieved by selecting 90 cirrhotic PHT patients who underwent transjugular intrahepatic portosystemic shunt in our hospital from June 2015 to September 2019. Fifty healthy people who had a physical examination in the hospital in the same period were selected as the control group. The liver hemodynamic parameters of two groups were measured by Doppler ultrasound, and the cirrhotic PHT patients were graded by the Child–Pugh grading method to evaluate the liver function and measure the PVP value. The results showed that both the central portal vein velocity (PVV) and splenic vein velocity (SVV) of the PHT group were lower than those of the control group. Also, the portal vein diameter (PVD), portal venous flow and splenic vein diameter (SVD) were higher than those of the control group (all P s 0.05). Among liver function graded PHT patients, the PVD, PVV, SVD and SVV were significantly different (all P s 0.05). Furthermore, the PVP of patients with liver function grades A, B and C was 38.9 ± 1.4, 40.6 ± 5.1 and 42.5 ± 4.8?cmH 2 O, respectively, with a significant difference. It can be concluded from this study that Doppler ultrasound can be used as a tool for clinical assessment of PHT in cirrhosis patients. Doppler ultrasound showed a good prospect in noninvasive detection of PHT in cirrhosis; however, this technique needs application on large sample population study to validate the results.
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机译：病毒和酒精性丙型肝炎引起的肝硬化是门静脉高血压（PHT）的重要原因。 PHT并发症的发生率与门静脉压（PVP）成正比，PVP及其血流动力指标的临床研究对于决定PHT的治疗策略具有重要意义。目前正在开发各种技术以降低门位压力，但可能发生血流动力学副作用。在本文中，研究了肝硬化患者的血流动力学指标，探讨了指数和PVP之间的相关性，并评估了多普勒超声在测量PHT患者PVP中的临床价值。这是通过选择从2015年6月至2019年6月到2019年6月在我们的医院接受过副医院肝内PortoSystemicsssicssstststsystystemicsssstststsystemics的肝硬化的患者实现了。通过多普勒超声测量两组的肝血流动力学参数，肝硬化的PHT患者被儿童-PPGR分级方法进行评分，以评估肝功能并测量PVP值。结果表明，PHT组的中央门静脉速度（PVV）和脾静脉速度（SVV）低于对照组。此外，门静脉直径（PVD），门静脉流动和脾静脉直径（SVD）高于对照组（所有P S <0.05）。在肝功能分级PHT患者中，PVD，PVV，SVD和SVV显着不同（所有P S <0.05）。此外，肝功能等级A，B和C患者的PVP分别为38.9±1.4,40.6±5.1和42.5±4.8℃，分别具有显着差异。从该研究中可以得出结论，多普勒超声可以用作肝硬化患者肝病临床评估的工具。多普勒超声波在肝硬化中的非侵入性检测中显示出良好的前景;然而，这种技术需要在大型样本群体研究中应用验证结果。
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