Abstract Background The Staffordshire Bull Terrier is a popular dog breed in the UK but there is limited reliable evidence on disorder predispositions and protections within the breed. Using anonymised veterinary clinical data from the VetCompass? Programme, this study aimed to identify common disorders with predisposition and protection in the Staffordshire Bull Terrier. The study hypothesised that Staffordshire Bull Terriers would have higher odds of aggression compared with non-Staffordshire Bull Terriers. Results The clinical records of a random sample of dogs of all types were reviewed to extract the most definitive diagnoses for all disorders existing during 2016. A combined list from the 30 most common disorders in Staffordshire Bull Terriers and the 30 most common disorders in non-Staffordshire Bull Terriers was generated. Multivariable logistic regression was used to report the odds of each of these disorders in 1304 (5.8%) Staffordshire Bull Terriers compared with 21,029 (94.2%) non-Staffordshire Bull Terriers. After accounting for confounding, Staffordshire Bull Terriers had significantly increased odds of 4/36 (11.1%) disorders compared to non-Staffordshire Bull Terriers with highest odds for seizure disorder (OR 2.06; 95% CI 1.24 to 3.40; p =?0.005). Conversely, Staffordshire Bull Terriers had reduced odds of 5/36 (13.9%) disorders, with lowest odds for patellar luxation (OR 0.15; 95% CI 0.04 to 0.61; p =?0.008). There was no significant difference in the odds of aggression between Staffordshire Bull Terriers compared with non-Staffordshire Bull Terriers (OR 1.09; 95% CI 0.75 to 1.58; p =?0.644). Conclusions This study provides a reliable evidence base of breed-specific disorder predispositions and protections that can be used by breeders to optimise breeding decisions. The findings can assist prospective owners of Staffordshire Bull Terriers to make informed decisions when acquiring a dog. From the relative number of predispositions to protections identified, there is no evidence that Staffordshire Bull Terriers have higher overall health problems than non-Staffordshire Bull Terriers.
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机译：摘要背景斯塔福德郡斗牛犬是英国的一只受欢迎的狗品种，但有限的可靠证据有关该品种内的紊乱易感性和保护的证据。使用vetcompass的匿名兽医临床数据？课程，本研究旨在识别斯塔福德郡斗牛犬的易感与保护常见疾病。与非斯塔福德郡斗牛犬相比，假设斯塔福德郡斗牛犬将具有更高的侵略性的几率。结果综述了所有类型随机样本犬样品的临床记录，提取2016年所有疾病的最明确的诊断。斯塔福德郡斗牛犬的30个最常见疾病的组合清单和非常见疾病生成斯塔福德郡斗牛犬。多变量逻辑回归用于在1304年（5.8％）斯塔福德郡斗牛区（5.8％）的斯塔福德郡斗牛犬报告每项疾病的几率。与21,029（94.2％）非斯塔福德郡斗牛犬相比。在收集混淆后，与非斯塔福德郡牛仔犬相比，斯塔福德郡斗牛犬的几率明显增加了4/36（11.1％）疾病的疾病（或2.06; 95％CI 1.24至3.40; P = 0.005） 。相反，斯塔福德郡的斗牛犬减少了5/36（13.9％）疾病的赔率，髌骨型缺陷最低（或0.15; 95％CI 0.04至0.61; P = 0.008）。与非斯塔福德郡斗牛犬（或1.09; 95％CI 0.75至1.58; P = 0.644），斯塔福德郡斗牛犬之间的侵略几率没有显着差异。结论本研究提供了一种可靠的繁殖疾病易感性倾向和保护，可由育种者使用，以优化育种决策。调查结果可以帮助斯塔福德郡斗牛犬的预期所有者在收购狗时做出明智的决定。从识别的相对次数到所识别的保护，没有证据表明斯塔福德郡斗牛犬的整体健康问题比非斯塔福德郡斗牛犬更高。
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