The effect of sequential treatments on circulating microRNAs related to bone metabolism in women with postmenopausal osteoporosis

摘要

Background: Depending on osteoporosis severity a long-term treatment, often as a sequential regimen, may be required. The serum expression of microRNAs (miRs) related to bone metabolism is potentially affected by anti-osteoporotic treatment. Here, we investigated the effect of sequential treatments on microRNA expression profile in the serum.