A 66-year-old woman was seen with a polypoid lesion found on screening colonoscopy in the appendiceal orifice (Fig. 1). A biopsy specimen could not be taken owing to the submucosal location of the lesion. On repeated colonoscopy, a partially inverted appendix was visualized. Possible carcinoid lesion was included in the differential diagnosis, as was a potential submucosal lesion.
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