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首页> 外文期刊>PLOS Neglected Tropical Diseases >An insight into the salivary gland and fat body transcriptome of Panstrongylus lignarius (Hemiptera: Heteroptera), the main vector of Chagas disease in Peru
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An insight into the salivary gland and fat body transcriptome of Panstrongylus lignarius (Hemiptera: Heteroptera), the main vector of Chagas disease in Peru

机译:洞察门大麻(Hemiptera:Hetucoctera),秘鲁赤曲疾病的主要载体洞察唾液腺和脂肪体转录组

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摘要

This work describes an in-depth salivary and fat body transcriptome from the triatomine P. lignarius, the main vector of Chagas disease in Peru. Following “de novo” assembly of over 160 million reads, 11 thousand coding sequences were obtained, 9,013 of which were submitted to GenBank. Those over expressed in the salivary glands or fat bodies were identified, leading to a detailed insight of the specificities of each organ. This work will serve future scientists not only for its increased knowledge on triatomine proteins, but also for its public protein sequences that will serve scientists as a target database in mass spectrometry experiments aiming at the identification of P. lignarius salivary pharmacological peptides or immunological targets of vector exposure.
机译:这项工作描述了来自秘鲁的Chagas病的主要载体的Triatomine P. Lignarius的深入唾液和脂肪体转录组。遵循“De Novo”组装超过1.7亿令吉,获得了11000个编码序列,其中9,013名已提交给Genbank。确定在唾液腺或脂肪体中表达的那些,导致对每个器官的特异性的详细介绍。这项工作将不仅为未来的科学家而言,不仅可以增加对Tratiatomine蛋白的知识,而且还可于其公共蛋白质序列,该蛋白质序列将在旨在鉴定鉴定P.Lignarius药理学肽或免疫学靶标中的质谱实验中的靶数据库。矢量曝光。

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