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Strengthening Neglected Tropical Disease Research through Enhancing Research-Site Capacity: An Evaluation of a Novel Web Application to Facilitate Research Collaborations

机译:通过提高研究现场能力来加强被忽视的热带病研究:评估新型网站申请,以促进研究合作

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The increasing number of clinical trials in developing countries brings unique challenges, including highly customised research infrastructure and narrow research focus. Many research sites have been equipped for one specific trial or disease area, often for a particular sponsor, with little consideration to subsequent diversification or sustainability [1]–[4]. Furthermore, the diseases studied in developing countries are seven to eight times more likely to be of relevance to developed countries than to developing countries [5],[6]. Accordingly, research sites are often only equipped to carry out research on diseases that are most relevant to developed nations—for example, noncommunicable diseases—rather than addressing local priority issues [7], [8].
机译:发展中国家的临床试验越来越多的挑战带来了独特的挑战,包括高度定制的研究基础设施和狭隘的研究重点。许多研究网站已经为一个特定的试验或疾病区域配备了一个特定的赞助商,几乎没有考虑到随后的多样化或可持续性[1] - [4]。此外,发展中国家研究的疾病与发达国家有关的七到八倍,而不是发展中国家[5],[6]。因此,研究部位通常仅配备对发达国家最相关的疾病的研究 - 例如,非传染性疾病 - 而不是解决局部优先问题[7],[8]。

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