PLATELET FUNCTION ASSESSMENT AMONG CHILDREN WITH CONGENITAL CYANOTIC HEART DISEASE PRESENTING IN TERTIARY CARE HOSPITAL LAHORE

摘要

Objective: The objective of this study was to determine the frequency of platelet dysfunction in congenital cyanotic heart diseases patients presenting to a tertiary care hospital in Lahore. Methodology: A cross sectional survey was carried out from March 2018 to February 2019 in children hospital Lahore. Patients of congenital cyanotic heart disease who fulfilled the inclusion were selected after taking informed consent. Aggregation ability of platelet rich plasma was tested by collagen (1.25μg/ml), ristocetin (1.2mg), epinephrine (5μM) and ADP (2.5μM). Results: There were one hundred and eighty-seven patients of congenital cyanotic heart disease in our study. The minimum age was 1 year and maximum age was 15 years with a mean age 8.02 ± 4.31 years. Platelet dysfunction was diagnosed in 60.4% patients. Conclusion: Platelet dysfunction was found to be high among patients of congenital cyanotic heart diseases.