THE ROLE OF ALUMINUM IN THE SYMPTOMATOLOGYOF ATTENTION DEFICIT HYPERACTIVITY DISORDERCHILDREN

摘要

ALUMINUM IS A CHEMICAL ELEMENT ATOMIC NUMBER 13. IT IS WHITE-SILVER, INSOLUBLE INWATER UNDER NORMAL CONDITIONS. DESPITE ITS NATURAL ABUNDANCE, ALUMINUM HAS NOKNOWN BIOLOGY FUNCTION. IT IS A TOXIC RESIDUE, ALUMINUM SULPHATE HAVING AN LD50 OF6207 MG/KG BODY, CORRESPONDING TO 500 GRAMS PER 80 KG PERSON. EXTREMELY ACUTETOXICITY WITHOUT HARM TO HEALTH IS OF INTEREST IN VIEW OF THE WIDESPREAD OCCURRENCEOF THE ELEMENT IN THE ENVIRONMENT AND IN TRADE7. TOXICITY CAN BE TRACKED AFTERDEPOSITION INTO THE BONES AND THE CENTRAL NERVOUS SYSTEM AND IS PARTICULARLY HIGH INPATIENTS WITH RENAL INSUFFICIENCY. BECAUSE ALUMINUM COMPETES WITH CALCIUM FORABSORPTION, INCREASED ALUMINA CAN CONTRIBUTE TO OSTEOPENIA, PRETERM AND GROWTHRETARDATION. IN VERY HIGH DOSES, ALUMINUM CAN CAUSE NEURO TOXICITY ASSOCIATED WITHALTERED FUNCTION OF THE BLOOD-BRAIN BARRIER.