Broad ligament Extraintestinal Gastrointestinal Stromal Tumor (EGIST): Case report and brief overview of EGIST

摘要

Gastrointestinal stromal tumor (GIST) represents the most common soft tissue sarcoma of the gastrointestinal (GI) tract. These tumors however are rare as they only account for 1% of all GI malignancies. The most common sites of origin are the stomach (70%) and small in- testine (30%), followed by the duodenum (5%), rectum (4%), eso- phagus (1%), colon and appendix (1%) (Cheng et al., 2019). It is thought that GIST originates in the interstitial cells of Cajal. Miettinen in 1999 was the first to describe GIST arising outside of the GI tract, named extra intestinal gastrointestinal stromal tumor (EGIST) (Miettinen et al., 1999). The main distinction between GIST and EGIST is the primary site of tumor origin. EGIST originating from locations outside of the GI tract such as retroperitoneum, mesentery, and omentum have been reported. Limited studies to date have reported EGIST originating from mullerian structures (Cheng et al., 2019; Weppler and Gaertner, 2005).