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Effects of Acupuncture on the Outcomes of Assisted Reproductive Technology: An Overview of Systematic Reviews

机译:针刺对辅助生殖技术结果的影响:系统评价概述

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Objectives. To conclude the evidence from systematic reviews (SRs) and meta-analyses assessing the effectiveness of acupuncture to treat couples with subfertility undergoing ART. Methods. We searched the major databases from their inception to March 2018 PubMed, Embase, The Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, Chongqing VIP, and Sino-Med (the Chinese database). The primary outcomes of the overview were live birth and clinical pregnancy, and secondary outcomes were ongoing pregnancy, miscarriage, and adverse events. Study selection, quality assessment, and data extraction were performed independently by two review authors. Review methodological quality was assessed by using the AMSTAR tool, and the quality of the evidence was rated by GRADE methods. Results. Eleven systematic reviews were included and published between 2009 and 2017. Our study showed that the acupuncture treatment seems to be a useful tool to improve the clinical pregnancy rate in patients who undergo assisted reproduction therapy. However, there was no evidence that acupuncture had any effect on live birth rate, ongoing pregnancy rates, or miscarriage regardless of whether acupuncture was performed around the time of oocyte retrieval or around the day of embryo transfer; this evidence is inconclusive because of the low quality of the included studies. Conclusions. The evidence for acupuncture to treat couples with subfertility undergoing ART remains unclear. Further research is needed, with high-quality trials undertaken and reported.
机译:目标。缔结从系统评价(SRS)和荟萃分析的证据评估针灸治疗伴侣的患者的有效性。方法。我们将主要数据库从他们的成立中搜索到2018年3月PubMed,Embase,Cochrane图书馆,中国国家知识基础设施(CNKI),万芳数据库,重庆VIP和Sino-Med(中文数据库)。概述的主要结果是生育和临床怀孕,二次结果正在进行怀孕,流产和不良事件。学习选择,质量评估和数据提取由两位审查作者独立进行。通过使用AMSTAR工具评估方法质量,证据质量评估为等级方法。结果。在2009年至2017年期间,包括并发布11个系统评价。我们的研究表明,针灸治疗似乎是一种有用的工具,可以提高接受辅助再生疗法的患者的临床妊娠率。然而,没有证据表明,无论针灸是否在卵母细胞检索时或胚胎转移到当天围绕胚胎转移周围进行针灸,针灸都没有证据表明对活率,持续的妊娠率或流产。由于所纳入的研究质量低,此证据是不确定的。结论。针灸治疗夫妇与经过艺术的患者治疗夫妇的证据仍不清楚。需要进一步研究,并进行高质量的试验并报告。

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