The Effect ofChanna striatus(Haruan) Extract on Pain and Wound Healing of Post-Lower Segment Caesarean Section Women

摘要

Channa striatushas been consumed for decades as a remedy to promote wound healing by women during postpartum period. The objectives of this study were to compare postoperative pain, wound healing based on wound evaluation scale (WES), wound cosmetic appearance based on visual analogue scale (VAS) scores and patient satisfaction score (PSS), and safety profiles betweenC. striatusgroup and placebo group after six weeks of lower segment caesarean section (LSCS) delivery. A randomised, double-blind, placebo-controlled study was conducted. Subjects were randomised in a ratio of 1 : 1 into either theC. striatusgroup (500 mg daily) or placebo group (500 mg of maltodextrin daily). 76 subjects were successfully randomised, with 38 in theC. striatusgroup and 35 in the placebo group. There were no significant differences in postoperative painp=0.814and WESp=0.160between theC. striatusand placebo groups. However, VAS and PSS in theC. striatusgroup were significantly better compared with the placebo group (p=0.014andp<0.001, resp.). The safety profiles showed no significant differences between the groups. In conclusion, six-week supplementation of 500 mg ofC. striatusextract showed marked differences in wound cosmetic appearance and patient’s satisfaction and is safe for human consumption.