(S)-2-[(4-Fluoro-phen-yl)formamido]-3-phenyl-propanoic acid

摘要

The title compound, C 16 H 14 FNO 3 , was synthesized via solid phase methods; it exhibits monoclinic ( P 2 1 ) symmetry at room temperature. The two independent mol-ecules that comprise the asymmetric unit display distinct torsion angles of 173.2?(2) and 72.6?(2)° along the central sp 3 C—N bond. In the crystal, hydrogen bonding through N—H?O contacts couples the asymmetric unit mol-ecules into pairs that align in layers extending parallel to (100) via additional O—H?O inter-actions. The phenyl ring of one independent mol-ecule was found to be disordered over two sets of sites in a 0.55?(3):0.45?(3) ratio.