Surface characteristics of and in vitro behavior of osteoblast-like cells on titanium with nanotopography prepared by high-energy shot peening

摘要

Background and methods: Commercial pure titanium with nanotopography was prepared via a high-energy shot-peening (HESP) technique. The surface characteristics were evaluated, and the preliminary cell responses to the nanotopographical surface were investigated.Results: The nanotopographical surface layer on titanium was successfully processed by HESP. The average nanoscale grains were approximately 60?nm in diameter and they were nonhomogeneously distributed on the surface. MG-63 cells with an osteogenic phenotype were well adhered and well spread on the nanostructured surface. Compared to the original polished control, the nanotopographical surface highly improved the adhesion, viability, and differentiation of MG-63 cells.Conclusion: Titanium with nanotopography achieved by HESP has good cytocompatibility and shows promise for dental implant applications.