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首页> 外文期刊>International Journal of General Medicine >Pulmonary Function Tests and Their Associated Factors Among Type 2 Diabetic Patients at Jimma Medical Center, in 2019;?Comparative Cross-Sectional Study
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Pulmonary Function Tests and Their Associated Factors Among Type 2 Diabetic Patients at Jimma Medical Center, in 2019;?Comparative Cross-Sectional Study

机译:2019年,JIMMA医学中心2型糖尿病患者中肺功能试验及其相关因素;?比较横截面研究

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Background: The presence of widespread lung microvascular circulation and abundant connective tissue with a large reserve raises the possibility that the lung may be a target organ of the pathologic processes induced by type 2 diabetes. Pulmonary function tests (PFTs) are noninvasive medical tests that show how well the lungs are working. Objective: The aim was to compare pulmonary function tests (PFTs) and their associated factors among type 2 diabetic patients and non-diabetics at Jimma Medical Center (JMC). Methods: A comparative cross-sectional study was conducted at JMC, Jimma, Southwest Ethiopia among 298 study participants from April 1?to May 30, 2019. A face-to-face interview with semi-structured questionnaire was conducted. Forced vital capacity (FVC), forced expiratory volume in one second (FEVsub1/sub), ratio of FEVsub1/sub/FVC, peak expiratory flow (PEF), and forced expiratory flow (FEFsub25? 75/sub) were recorded by using a digital Spirometer. Independent samples t -test, simple and multiple linear regression analysis were used. Results: The present study indicated that means of the PFTs among type 2 diabetics were significantly reduced when compared to their matched non-diabetics (FVC (%) (m=73.7± 13.8 vs m=93.8± 12.3), FEVsub1/sub (%) (m=76.4± 13.4 vs m=93.3± 12.4), FEVsub1/sub/FVC (%) (m=78.99± 11.4 vs m=96.6± 9.33), PEF (L/s) (m=3.91± 0.28 vs m=5.03± 0.35), and FEFsub25– 75/sub (L/s) (m=2.89± 0.75 vs m=3.39± 0.82)). This study also indicated that body mass index (BMI) (β=? 1.93, P 0.001) and fasting blood sugar (FBS) (β=? 0.22, P 0.001) were negative predictors of FVC%. BMI (β=? 1.93, P 0.001) and FBS (β=? 0.29, P 0.001) were negative predictors of FEV1%. BMI (β=? 1.403, P 0.001) was a negative predictor of mean FEVsub1/sub/FVC. BMI (β=? 1.39 P 0.001) and FBS (β=? 0.15, P 0.001) were negative predictors of mean PEF?(L/s). BMI (β=? 0.075, P 0.001) and FBS (β=? 0.075, P 0.001) were negative predictors of FEFsub25– 75/sub (L/s). Conclusion: The present study showed that there were significantly reduced mean scores of FVC, FEVsub1/sub, FEVsub1/sub/FVC, PEF, and?FEFsub25– 75/sub among type 2 diabetic patients as compared to non-diabetic participants. The FBS and BMI were independent risk factors of the PFTs among the diabetics, unlike among non-diabetic participants.
机译:背景:具有大储备的广泛肺部微血管循环和丰富的结缔组织引发了肺部可以是由2型糖尿病诱导的病理过程的靶器官的可能性。肺功能测试(PFT)是非侵入性医学测试,表明肺部有多工作。目的:目的是将肺功能试验(PFT)及其在Jimma Medical Centre(JMC)中的2型糖尿病患者和非糖尿病患者之间的相关因素进行比较。方法:在4月1日的298名埃塞俄比亚JMC,JMC,JMC,JMC进行了比较横截面研究?到2019年5月30日。对半结构化问卷的面对面面试进行了面对面。强制生命能力(FVC),强制呼气量在一秒(FEV 1 ),FEV 1 / fvc,峰值呼气流(PEF)的比例,并强制呼气流(使用数字肺部计记录了FEF 25?75 )。使用独立的样本T -Test,简单,多元线性回归分析。结果:本研究表明,与其匹配的非糖尿病患者(FVC(%)(M = 73.7±13.8 VS M = 93.8±12.3),FEV 1相比,本研究表明,2型糖尿病患者之间的方法显着降低了显着降低了(%)(m = 76.4±13.4 vs m = 93.3±12.4),FEV 1 / fvc(%)(m = 78.99±11.4 vs m = 96.6±9.33),PEF (L / S)(m = 3.91±0.28 Vs m = 5.03±0.35),FEF 25- 75 (L / s)(m = 2.89±0.75 Vs m = 3.39±0.82)) 。本研究还表明,体重指数(BMI)(BMI)(β=β1.93,P <0.001)和空腹血糖(FBS)(β= 0.22,P <0.001)是FVC%的负预测因子。 BMI(β=β1.93,P <0.001)和FBS(β= 0.29,P <0.001)是FEV1%的负预测因子。 BMI(β=α1.403,P <0.001)是平均FEV 1 / fvc的负预测器。 BMI(β=β1.39p <0.001)和FBS(β= 0.15,P <0.001)是平均pEF的阴性预测因子?(L / s)。 BMI(β= 0.075,P <0.001)和FBS(β= 0.075,P <0.001)是FEF 25-75 (L / s)的负预测因子。结论:本研究表明,FVC的平均分数显着降低,FEV 1 / FVC,PEF和?FEF 25- 75 <与非糖尿病参与者相比,2型糖尿病患者中的/亚次>与非糖尿病参与者不同,FBS和BMI是糖尿病患者中PFT的独立危险因素。

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