Score for neonatal acute physiology perinatal extension II in predicting neonatal mortality in the neonatal intensive care unit

摘要

Background and Aim: Very low birth weight (VLBW) neonates constitute approximately 4%–7% of all live births and their mortality is very high (50%). There has been an effort in recent times to develop the severity score for the illness like score for neonatal acute physiology perinatal extension II (SNAPPE-II) score so that it is possible to prevent, particularly aiming the improvement of newborn children care. The study aimed to determine the validity of SNAPPE-II in predicting the VLBW neonates' mortality risk in the neonatal intensive care unit (NICU) at teaching hospital of Raipur, Chhattisgarh. Materials and Methods: This was a hospital-based prospective study carried out among all premature newborns weighing 1500 g and more than 26 weeks admitted to the NICU with a sample size of 129. The variables of SNAPPE-II score were prospectively recorded within 12 h of admission, and their outcome was monitored till 28 days postbirth period. All tests were performed at a 5% level of significance. Results: The SNAPPE II score of the dead neonates was significantly higher than the surviving neonates (43.6 ± 17.25 vs. 18.2 ± 13.09; P 0.001), and the receiver operating characteristics (ROC) showed that discriminating ability of SNAPPE-II score was 0.857 (good). The best cutoff for SNAPPE II score in predicting neonatal mortality on charting the ROC was 31. Conclusion: The present study was conducted to specifically design to evaluate the validity of SNAPPE II score as predictor of neonatal mortality in VLBW infants and helps in prioritizing them so we can intervene and prevent mortality in these neonates.