Triptycene-Based and Schiff-Base-Linked Porous Networks: Efficient Gas Uptake, High CO2/N2 Selectivity, and Excellent Antiproliferative Activity

摘要

A set of unique triptycene-based and organic Schiff-base-linked polymers (TBOSBL s) are conveniently synthesized in which triptycene motifs are connected with 1,3,5-triformylphloroglucinol units via Schiff-base linkages. TBOSBL s are amorphous, thermally stable with a reasonable surface area (SA_(BET) up to 649 m~(2)/g), and have abundant nanopores (pore size < 100 nm). TBOSBL s are good sorbents for small gas molecules (such as CO_(2), H_(2), and N_(2)) and they can selectively capture CO_(2) over N_(2). Additionally, TBOSBL s show superior antiproliferative activity against human colorectal cancer cells relative to previously reported covalent organic frameworks (COFs). The mechanism of cell death is also studied elaborately.