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Investigation Report of cVDPV2 Outbreak in Bokh Woreda of Dollo Zone, Somali Regional State, Ethiopia

机译:埃塞俄比亚索马里地区国家北极区Bokh Woreda的CVDPv2爆发调查报告

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Background. Poliovirus isolates detected in persons or in the environment can fall into three major categories: wild, Sabin and Sabin-like, or vaccine-derived. Detection of wild or vaccine-derived poliovirus may constitute an emergency, which can be categorized as an event that can lead to an outbreak, depending on characteristics of the isolate and the context in which it appears. The aim of the study was investigation report of cVDPV2 outbreak in Bokh woreda of Dollo Zone, Somali regional state, Ethiopia. Methods. A team of experts drawn from different organizations was deployed to Bokh woreda to make detailed field investigation from May 25 to June 17, 2019. By using standard World Health Organization polio outbreak investigation checklist, document review of surveillance, immunization, and clinical data related to the case was made. Key informant’s interview was made to health professionals, managers, parents of case, woreda and kebele leaders, religious leaders, and HEWs related to acute flaccid paralysis outbreak. Result. The notified AFP case was a 39-month-old female from Angalo kebele of Bokh woreda, Dollo Zone. On 19th May 2019, the patient developed high grade fever and was taken to Angalo Health Post on 20th May 2019. As per the examination by a health extension worker, the child had high grade fever and neck stiffness with preliminary diagnosis of meningitis for which ceftriaxone injection was prescribed. Contact sample was taken from three children on 28th May 2019 and 29th May 2019 and was sent to Addis Ababa National Polio Laboratory. All contact stool samples were found to be positive for poliovirus type 2 and referred for sequencing in National Institute of Communicable Diseases (NICD), South Africa, the Regional Polio Reference Laboratory. Conclusion and Recommendation. The clinical presentation of the cases is compatible with poliovirus infection, improving the quality and coverage of supplementary polio immunization activities through proper planning; strict supervision and follow-up can reduce the occurrence of acute flaccid paralysis.
机译:背景。在人或环境中检测到的脊髓灰质炎病毒分离物可以分为三大类:野生,西班牙和Sabin样,或疫苗衍生。野生或疫苗衍生的脊髓灰质病毒的检测可以构成紧急情况,这可以作为可能导致爆发的事件进行分类,这取决于隔离的特征和所出现的上下文。该研究的目的是COKH Woroda的CVDPv2爆发的调查报告,埃塞俄比亚索马里地区国家的北极区。方法。从不同组织中汲取的专家团队部署到Bokh Woreda,从5月25日至6月17日开始进行详细的实地调查。通过使用标准世界卫生组织脊髓灰质炎疫情调查清单,记录监测,免疫和临床资料案件是制作的。主要线人的采访是对健康专业人士,经理,案件,案件的父母,宗教领袖,宗教领袖和与急性弛缓性瘫痪爆发有关的Hews。结果。通知的AFP案例是来自博纳尔·克贝尔的一个39个月大的女性,博克尔·沃勒州,美元区。 2019年5月19日,患者于2019年5月20日发育了高年级发烧,并被采用至安马罗卫生职位。根据卫生拓展工人的检查,儿童具有高年级的发热和颈部僵硬,初步诊断脑膜炎的脑膜炎预先注射。联系方式于2019年5月28日和2019年5月29日起从三名儿童中获取,并被送到Addis Ababa National Polio实验室。发现所有接触凳样品都被发现为脊髓灰质炎病毒2型阳性,并在国家传染病研究所(NICD),南非区域脊髓灰质炎参考实验室中提到测序。结论和推荐。病例的临床介绍与Poliovirus感染相容,通过适当的规划提高了补充脊髓灰质炎免疫活动的质量和覆盖范围;严格的监督和随访可以减少急性弛缓性瘫痪的发生。

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