The effects of two weeks high-intensity interval training on fasting glucose, glucose tolerance and insulin resistance in adolescent boys: a pilot study

摘要

Current evidence of metabolic health benefits of high-intensity interval training (HIIT) are limited to longer training periods or conducted in overweight youth. This study assessed 1) fasting and postprandial insulin and glucose before and after 2 weeks of HIIT in healthy adolescent boys, and 2) the relationship between pre intervention health outcomes and the effects of the HIIT intervention. Seven healthy boys (age:14.3?±?0.3 y, BMI: 21.6?±?2.6, 3 participants classified as overweight) completed 6 sessions of HIIT over 2 weeks. Insulin resistance (IR) and blood glucose and insulin responses to a Mixed Meal Tolerance Test (MMTT) were assessed before (PRE), 20?h and 70?h after (POST) the final HIIT session. Two weeks of HIIT had no effect on fasting plasma glucose, insulin or IR at 20?h and 70?h POST HIIT, nor insulin and glucose response to MMTT (all P??0.05). There was a strong negative correlation between PRE training IR and change in IR after HIIT (r?=???0.96, P??0.05). Two weeks of HIIT did not elicit improvements to fasting or postprandial glucose or insulin health outcomes in a group of adolescent boys. However the negative correlation between PRE IR and improvements after HIIT suggest that interventions of this type may be effective in adolescents with raised baseline IR.