Effect of altering breathing frequency on maximum voluntary ventilation in healthy adults

摘要

Compared to other pulmonary function tests, there is a lack of standardization regarding how a maximum voluntary ventilation (MVV) maneuver is performed. Specifically, little is known about the variation in breathing frequency (fR) and its potential impact on the accuracy of test results. This study examines the effect of several preselected values for fR and one self-selected fR (fRself) on MVV. Ten participants performed MVV maneuvers at various fR values, ranging from 50 to 130 breaths·min??1 in 10 breaths·min??1 intervals and at one fRself. Three identical trials with 2-min rest periods were conducted at each fR, and the sequence in which fR was tested was randomized. Ventilation and related parameters were measured directly by gas exchange analysis via a metabolic measurement system. A third-order polynomial regression analysis showed that MVV?=???0.0001(fR)3?+?0.0258(fR)2–1.38(fR)?+?96.9 at preselected fR and increased up to approximately 100 breaths·min??1 (r2?=?0.982, P?