Preliminary study of Alzheimer's Disease diagnosis based on brain electrical signals using wireless EEG

摘要

Thisresearchaimstostudybrain'selectricalsignalsrecordedusingEEGasabasisforthediagnosisofpatientswithAlzheimer'sDisease(AD).ThesubjectsconsistedofpatientswithAD,andnormalsubjectsareusedasthecontrol.Brainsignalsarerecordedfor3minutesinarelaxedconditionandwitheyesclosed.Thedataisprocessedusingpowerspectralanalysis,brainmappingandchaostesttoobservethelevelofcomplexityofEEG'sdata.Theresultsshowashiftinthepowerspectralinthelowfrequencyband(deltaandtheta)inADpatients.Theincreaseofdeltaandthetaoccursinlobusfrontalareaandlobusparietalrespectively.However,thereisadecreaseofalphaactivityinADpatientswhereinthecaseofnormalsubjectswithrelaxedcondition,brainalphawavedominatestheposteriorarea.Thisisconfirmedbytheresultsofbrainmapping.WhiletheresultsofchaosanalysisshowthattheaveragevalueofMMLEislowerinADpatientsthaninnormalsubjects.ThelevelofchaosassociatedwithneuralcomplexityinADpatientswithlowerneuralcomplexityisduetoneuronaldamagecausedbythebetaamyloidplaquesandtauproteininneurons...