Idiopathic thrombocytopenic purpura associated with Helicobacter pylori infection in a patient with liver cirrhosis accompanying hepatitis B

摘要

Thrombocytopenia is a major hematological disorder observed in patients with liver cirrhosis (LC). The condition is primarily attributed to hypersplenism, which is accompanied by an increased sequestration and accelerated destruction of platelets in the pathologically enlarged and congested spleen.1–3 Patients with LC are also frequently subject to various disorders of the gastric mucosa, and peptic lesions in the gastroduodenal mucosa have been observed more often in cirrhotic patients than in controls.