Tuck-in Lamellar keratoplasty with an lenticule obtained by small incision lenticule extraction for treatment of Post- LASIK Ectasia

摘要

Corneal ectasia is a rare but serious post-operative complication of LASIK. Our main aim was to describe and evaluate the efficacy and safety of tuck-in lamellar keratoplasty with an lenticule obtained by SMILE for treatment of Post LASIK Ectasia. Tuck-in lamellar keratoplasty was performed on three post-LASIK cornea ectasia patients (three eyes) with central corneal thickness less than 400?μm. Each patient was monitored for at least 12 months. Our primary outcomes measured pre and post-operatively included: Anterior segment optical coherence tomography(AS-OCT), corneal topography and monitored by slit-lamp microscopy. The mean total corneal thickness preoperatively and 1?day, 1 month, 3 months and 12 months post-op were 360.00?±?32.07?μm, 590.00?±?10.00?μm, 536.67?±?11.54?μm, 523.33?±?37.85?μm, 466.67?±?41.63?μm. The mean lenticule implanted 1?day, 1 month, 3 months and 12 months post-op were 173.33?±?41.63?μm,136.67?±?25.16?μm, 133.33?±?40.41?μm, 130.00?±?17.32?μm. There was no evidence of immune rejection or other complications. Tuck-in lamellar keratoplasty with an lenticule obtained by SMILE seems to be a safe and alternative surgical approach in the treatment of post - LASIK cornea ectasia, especially for severe cases with cornea thickness less than 400?μm.