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The importance of parameter choice in modelling dynamics of the eye lens

机译:参数选择在眼镜动力学建模中的重要性

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The lens provides refractive power to the eye and is capable of altering ocular focus in response to visual demand. This capacity diminishes with age. Current biomedical technologies, which seek to design an implant lens capable of replicating the function of the biological lens, are unable as yet to provide such an implant with the requisite optical quality or ability to change the focussing power of the eye. This is because the mechanism of altering focus, termed accommodation, is not fully understood and seemingly conflicting theories require experimental support which is difficult to obtain from the living eye. This investigation presents finite element models of the eye lens based on data from human lenses aged 16 and 35 years that consider the influence of various modelling parameters, including material properties, a wide range of angles of force application and capsular thickness. Results from axisymmetric models show that the anterior and posterior zonules may have a greater impact on shape change than the equatorial zonule and that choice of capsular thickness values can influence the results from modelled simulations.
机译:镜片向眼睛提供屈光力,并且能够响应于视觉需求而改变眼焦点。随着年龄的增长,这种能力会下降。试图设计能够复制生物晶状体功能的植入物晶状体的当前生物医学技术尚不能为这种植入物提供所需的光学质量或改变眼睛的聚焦能力的能力。这是因为尚未完全了解改变焦点的机制(称为适应性),并且看似矛盾的理论需要实验支持,而这是很难从活着的眼睛中获得的。这项研究基于16岁和35岁人类晶状体的数据提出了眼晶状体的有限元模型,这些数据考虑了各种建模参数的影响,包括材料特性,大范围的作用力角度和囊厚度。轴对称模型的结果表明,前小带和后小带可能比赤道小带对形状变化的影响更大,并且囊厚度值的选择会影响建模模拟的结果。

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