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Nasopharyngeal Malt Lymphoma- A Case Report Of Rare Entity With Review Of Literature

机译:鼻咽麦芽淋巴瘤-一例罕见病报道并文献复习

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Mucosa associated lymphoid tissue confers the first line of defense in case of membranes which are directly exposed to the external environment. MALT lymphomas arising at these sites present diagnostic and therapeutic challenges, especially if arising from areas such as the nasopharynx, where adenoid hyperplasia is very commonly present as a mass. In the present case report, a 55 year old male presented to the medical emergency department with complaints of severe respiratory distress. Radiological and clinical evaluation revealed a mass; the biopsy was taken and sent for histopathological examination, which suggested a possibility of MALT lymphoma. This was subsequently proven on immunohistochemical studies, which showed positive staining for CD 20 and negative staining for CD 3, CD 5 and CD 43. Hence, a final diagnosis of low grade B-cell MALT lymphoma was made. A quick and comprehensive diagnosis of MALToma is desirable, as it is amenable to chemotherapeutic therapy.
机译:在膜直接暴露于外部环境的情况下,与粘膜相关的淋巴样组织赋予第一道防线。在这些部位出现的MALT淋巴瘤提出了诊断和治疗方面的挑战,特别是如果是由诸如鼻咽部这样的区域引起的,则其中腺样增生很常见。在本病例报告中,一名55岁的男性因严重呼吸窘迫而向医疗急诊科求诊。放射学和临床评估发现肿块;进行活检并送去进行组织病理学检查,提示可能存在MALT淋巴瘤。随后在免疫组织化学研究中证明了这一点,该研究显示CD 20呈阳性染色,CD 3,CD 5和CD 43呈阴性染色。因此,对低级B细胞MALT淋巴瘤做出了最终诊断。希望对MALToma进行快速,全面的诊断,因为它适合进行化学疗法。

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