Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression

Jianli Shi; Ying Zhao; Domenico Galati; Mark Winey; Michael W. Klymkowsky

首页> 外文期刊>Developmental biology >Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression

【24h】

Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression

机译：爪蟾在非洲爪蟾的睫毛装配，胚胎发育和基因表达的调节中的功能

获取原文

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Wntsignalingandciliogenesisarecorefeaturesofembryonicdevelopmentinarangeofmetazoans.Chibby(Cby),abasal-bodyassociatedprotein,regulatesβ-catenin-mediatedWntsignalinginthemousebutnotemDrosophila/em.HerewepresentananalysisofCby?sembryonicexpressionandmorphantphenotypesinemXenopuslaevis.Cby/emRNAissuppliedmaternally,negativelyregulatedbySnail2butnotTwist1,preferentiallyexpressedintheneuroectoderm,andregulatesβ-catenin-mediatedgeneexpression.ReducingCbylevelsreducedthedensityofmulticiliatedcells,thenumberofbasalbodiespermulticiliatedcell,andthenumbersofneuraltubeprimarycilia;italsoledtoabnormaldevelopmentoftheneuralcrest,centralnervoussystem,andpronephros,alldefectsthatwererescuedbyaCby-GFPchimera.ReductionofCbyledtoanincreaseinemWnt8a/emanddecreasesinemGli2/em,emGli3/em,andemShh/emRNAlevels.Many,butnotall,morphantphenotypesweresignificantlyreversedbytheWntinhibitorSFRP2.TheseobservationsextendourunderstandingofCby?sroleinmediatingthenetworkofinteractionsbetweenciliogenesis,signalingsystemsandtissuepatterning./p/div

机译：Wntsignalingandciliogenesisarecorefeaturesofembryonicdevelopmentinarangeofmetazoans.Chibby（CBY），abasal-bodyassociatedprotein，regulatesβ连环蛋白mediatedWntsignalinginthemousebutnot 果蝇 .HerewepresentananalysisofCby？sembryonicexpressionandmorphantphenotypesin Xenopuslaevis.Cby RNAissuppliedmaternally，negativelyregulatedbySnail2butnotTwist1，preferentiallyexpressedintheneuroectoderm，andregulatesβ联蛋白 - mediatedgeneexpression。 ReducingCbylevelsreducedthedensityofmulticiliatedcells，thenumberofbasalbodiespermulticiliatedcell，andthenumbersofneuraltubeprimarycilia; italsoledtoabnormaldevelopmentoftheneuralcrest，centralnervoussystem，andpronephros，alldefectsthatwererescuedbyaCby-GFPchimera.ReductionofCbyledtoanincreasein WNT8A anddecreasesin Gli2的，的Gli3 和的Shh < RNA水平。Wnt抑制剂SFRP2显着逆转了许多但并非所有的吗啡表型。这些观察结果是通过介导相互作用的网络之间的介导来延长对C的理解。起源，信号系统和组织模式。 展开▼

著录项

来源
《Developmental biology》 |2014年第2期|共页

作者
Jianli Shi; Ying Zhao; Domenico Galati; Mark Winey; Michael W. Klymkowsky;
展开▼

作者单位

展开▼

收录信息

原文格式 PDF

正文语种

中图分类生物科学;

关键词

相似文献

外文文献

中文文献

专利

1. Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression [J] . Shi Jianli, Zhao Ying, Galati Domenico, Developmental biology . 2014,第2期

机译：爪蟾在非洲爪蟾的睫毛装配，胚胎发育和基因表达的调节中发挥功能

2. Validation of novel reference genes for RT-qPCR studies of gene expression in Xenopus tropicalis during embryonic and post-embryonic development [J] . Dhorne-PolletS., ThélieA., PolletN. Developmental dynamics: an official publication of the American Association of Anatomists . 2013,第6期

机译：新参考基因的验证，用于RT-qPCR研究热带和非洲爪蟾胚胎和胚胎后发育过程中的基因表达

3. Differential expression of foxo genes during embryonic development and in adult tissues of Xenopus tropicalis [J] . Gene Expression Patterns: A Section of Mechanisms of Development . 2020,第期

机译：胚胎发育过程中Foxo基因的差异表达及杂耍杂耍成人组织

4. Development of Capillary Electrophoresis Mass Spectrometry for the Metabolic Investigation of Single Embryonic Cells in Xenopus laevis [C] . Sydney Morris, Rosemary M. Onjiko, Sally A. Moody, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：毛细管电泳质谱的研制Xenopus Laevis单一胚胎细胞代谢调查

5. Cadherin mediated F-actin assembly and the regulation of morphogenetic movements during Xenopus laevis development. [D] . Nandadasa, Sumeda. 2010

机译：钙粘蛋白介导的F-肌动蛋白装配和非洲爪蟾发育过程中形态发生运动的调节。

6. Chibby functions in Xenopus ciliary assembly embryonic development and the regulation of gene expression [O] . Jianli Shi, Ying Zhao, Domenico Galati, -1

机译：爪蟾在非洲爪蟾的睫毛装配胚胎发育和基因表达的调节中发挥功能

7. Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression [O] . Shi Jianli, Zhao Ying, Galati Domenico, 2014

机译：爪蟾在非洲爪蟾的睫毛装配，胚胎发育和基因表达的调节中发挥功能

1. XBP1在非洲爪蟾胚胎发育中的作用 [J] . 刘佳 ,李卉 ,冯娇娇 . 南京医科大学学报（自然科学版） . 2017,第001期

2. Fox家族在非洲爪蟾胚胎发育中的表达模式及作用 [J] . 申姗姗 ,任斐 ,陈晓虹 . 广东农业科学 . 2013,第007期

3. IRE1α通过UPR影响非洲爪蟾胚胎发育 [J] . 李昕昕 ,冯娇娇 ,侯道荣 . 南京医科大学学报（自然科学版） . 2011,第010期

4. 氟吗啉对非洲爪蟾胚胎发育的影响 [J] . 朱新萍 ,蔡磊明 ,蒋平安 . 农药 . 2007,第010期

5. 用DNA酶切小分子片段在非洲爪蟾卵中提取物中实现非细胞体系核装配 [J] . 蒋争凡 ,赵国燕 . 动物学报 . 1996,第004期

6. 全氟辛烷磺酸基化合物(PFOS)对非洲爪蟾(Xenopus laevis)胚胎发育的影响 [C] . 刘青坡 ,钱丽娟 ,郭素珍 . 第四届全国环境化学学术大会 . 2007

7. 热带爪蟾Dmrt5在早期胚胎发育中的功能研究 [A] . 陆怡 . 2010

1. 一种带有黄色或红色荧光蛋白标签的非洲爪蟾卵母细胞表达载体及应用 [P] . 中国专利： CN109055425B . 2021.10.29

2. 一类非洲爪蟾胰高血糖素样肽-1类似物及其应用 [P] . 中国专利： CN112724240A . 2021-04-30

3. Methods for Conditional and Inducible Transgene Expression to Direct the Development of Embryonic, Embryonic Stem, Precursor and Induced Pluripotent Stem Cells [P] . 外国专利： US2012047588A1 . 2012-02-23

机译：有条件和诱导型转基因表达的方法，以指导胚胎，胚胎干，前体和诱导多能干细胞的发展。

4. A method for increasing seed size and seed number in plants by transgenic overexpression of a gene associated with the growth and / or development of, during early embryonic development [P] . 外国专利： RU2008123381A . 2010-01-20

机译：一种通过在胚胎早期发育过程中转基因过度表达与生长和/或发育相关的基因来增加植物种子大小和种子数量的方法

5. Seed number and seed size has been increased through transgenic overexpression of occurrence and related genes occur in early embryonic development and / or [P] . 外国专利： JP2009519719A . 2009-05-21

机译：种子数量和种子大小通过转基因的过表达而增加，并且相关基因在早期胚胎发育和/或中发生

相关主题

Chibby functions in Xenopus ciliary assembly, embryonic development, and the regulation of gene expression

摘要

著录项

相似文献

相关主题

期刊订阅