Aym1, a mouse meiotic gene identified by virtue of its ability to activate early meiotic genes in the yeast Saccharomyces cerevisiae

Mira Malcov; Karen Cesarkas; Gil Stelzer; Sarah Shalom; Yosef Dicken; Yaniv Naor; Ronald S. Goldstein; Shira Sagee; Yona Kassir; Jeremy Don

首页> 外文期刊>Developmental biology >Aym1, a mouse meiotic gene identified by virtue of its ability to activate early meiotic genes in the yeast Saccharomyces cerevisiae

【24h】

Aym1, a mouse meiotic gene identified by virtue of its ability to activate early meiotic genes in the yeast Saccharomyces cerevisiae

机译：Aym1，一种小鼠减数分裂基因，其通过激活酿酒酵母中早期减数分裂基因的能力而鉴定

获取原文

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Ourunderstandingofthemolecularmechanismsthatoperateduringdifferentiationofmitoticallydividingspermatogoniacellsintospermatocyteslagswaybehindwhatisknownaboutotherdifferentiatingsystems.Giventheevolutionaryconservationofthemeioticprocess,wescreenedformouseproteinsthatcouldspecificallyactivateearlymeioticpromotersinemSaccharomycescerevisiae/emyeastcells,whenfusedtotheGal4activationdomain(Gal4AD).OurscreenyieldedtheemAym1/emgenethatencodesashortpeptideof45aminoacids.WeshowthataGal4ADndash;AYM1fusionproteinactivatesexpressionofreportergenesthroughthepromotersoftheearlymeiosis-specificgenesemIME2/emandemHOP1/em,andthatthisactivationisdependentontheDNA-bindingproteinUme6.emAym1/emistranscribedpredominantlyinmouseprimaryspermatocytesandingonadsoffemaleembryosundergoingthecorrespondingmeioticdivisions.Aym1immunolocalizedtonucleiofprimaryspermatocytesandoocytesandtospecifictypeAspermatogoniacells,suggestingitmightplayaroleintheprocessesleadingtomeioticcompetence.ThepotentialfunctionalrelationshipbetweenAYM1andyeastproteinsthatregulateexpressionofearlymeioticgenesisdiscussed./p/div

机译：Ourunderstandingofthemolecularmechanismsthatoperateduringdifferentiationofmitoticallydividingspermatogoniacellsintospermatocyteslagswaybehindwhatisknownaboutotherdifferentiatingsystems.Giventheevolutionaryconservationofthemeioticprocess，wescreenedformouseproteinsthatcouldspecificallyactivateearlymeioticpromotersin 酿酒酵母的yeastcells，whenfusedtotheGal4activationdomain（GAL4ad）.Ourscreenyieldedthe <位置> Aym1 的genethatencodesashortpeptideof45aminoacids.WeshowthataGal4ADndash; AYM1fusionproteinactivatesexpressionofreportergenesthroughthepromotersoftheearlymeiosis-specificgenes <位置> IME2 和 HOP1 < / em>，并且该激活依赖于DNA结合蛋白Ume6。 Aym1 主要在小鼠原代精子细胞和相应的减数分裂部位中被吞噬了下腹水肿。讨论了AYM1与调控早期减数分裂发生的表达的酵母蛋白之间的功能关系。 展开▼

著录项

来源
《Developmental biology》 |2004年第1期|共页

作者
Mira Malcov; Karen Cesarkas; Gil Stelzer; Sarah Shalom; Yosef Dicken; Yaniv Naor; Ronald S. Goldstein; Shira Sagee; Yona Kassir; Jeremy Don;
展开▼

作者单位

展开▼

收录信息

原文格式 PDF

正文语种

中图分类生物科学;

关键词

相似文献

外文文献

中文文献

专利

1. Aym1, a mouse meiotic gene identified by virtue of its ability to activate early meiotic genes in the yeast Saccharomyces cerevisiae. [J] . Malcov M, Cesarkas K, Stelzer G, Developmental biology . 2004,第1期

机译：Aym1，一种小鼠减数分裂基因，通过其激活酿酒酵母中早期减数分裂基因的能力而鉴定。

2. Systematic Mutagenesis of the Saccharomyces cerevisiae MLH1 Gene Reveals Distinct Roles for Mlh1p in Meiotic Crossing Over and in Vegetative and Meiotic Mismatch Repair [J] . Juan Lucas Argueso, Amanda Wraith Kijas, Sumeet Sarin, Molecular and Cellular Biology . 2003,第3期

机译：酿酒酵母MLH1基因的系统诱变揭示了Mlh1p在减数分裂穿越以及在营养和减数分裂失配修复中的独特作用。

3. A General Method for Identifying Recessive Diploid-Specific Mutations in Saccharomyces cerevisiae, Its Application to the Isolation of Mutants Blocked at Intermediate Stages of Meiotic Prophase and Characterization of a New Gene SAE2 [J] . Andrew H. Z. McKee, Nancy Kleckner Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 1997,第3期

机译：鉴定酿酒酵母隐性二倍体特异性突变的通用方法，其在分离减数分裂前期中期受阻突变体中的应用和新基因SAE2的鉴定

4. Assessing fluctuating evolutionary pressure in yeast and mammal evolutionary rate covariation using bioinformatics of meiotic protein genetic sequences [C] . Sunil Dehipawala, A. Nguyen, G. Tremberger Jr., Instruments, methods, and missions for astrobiology XVI . 2013

机译：利用减数分裂蛋白遗传序列的生物信息学评估酵母和哺乳动物进化速率协变中波动的进化压力

5. Regulation of middle meiotic gene expression by the Sum1 repressor in Saccharomyces cerevisiae. [D] . Ahmed, Noreen T. 2010

机译：Sum1阻遏物在酿酒酵母中对中间减数分裂基因表达的调节。

6. Systematic Mutagenesis of the Saccharomyces cerevisiae MLH1 Gene Reveals Distinct Roles for Mlh1p in Meiotic Crossing Over and in Vegetative and Meiotic Mismatch Repair [O] . Juan Lucas Argueso, Amanda Wraith Kijas, Sumeet Sarin, 2003

机译：酿酒酵母MLH1基因的系统诱变揭示了Mlh1p在减数分裂穿越以及在营养和减数分裂失配修复中的独特作用。

7. Aym1, a mouse meiotic gene identified by virtue of its ability to activate early meiotic genes in the yeast Saccharomyces cerevisiae [O] . Malcov Mira, Cesarkas Karen, Stelzer Gil, 2004

机译：Aym1，一种小鼠减数分裂基因，其通过激活酿酒酵母中早期减数分裂基因的能力而鉴定

1. 酿酒酵母减数分裂的事件和特异性基因 [J] . 李丽 . 生物技术通讯 . 2006,第004期

2. 减数分裂特异基因sycp1在小鼠精母细胞中的表达 [J] . 郭睿 ,于保锋 ,闫萍 . 山西医科大学学报 . 2008,第008期

3. 尝试在减数分裂中理解基因的分离定律和基因的自由组合定律 [J] . 蒋卫娟 . 科学大众（科学教育） . 2018,第007期

4. 雷州黑鸭早期卵巢卵泡发育规律及减数分裂基因表达研究 [J] . 邹坤 ,崔红艳 ,张少伟 . 黑龙江畜牧兽医（下半月） . 2019,第009期

5. 减数分裂关键基因Spo11和Mlh1在鲫鲤杂交鱼中的遗传分析 [J] . 朱辣 ,刘少军 ,张美文 . 南方农业学报 . 2021,第008期

6. 出生前后卵母细胞中的cAMP调控了小鼠第一次减数分裂早期发育和原始卵泡形成 [C] . 王怡婧 ,滕臻 ,李舸 . 全国动物生理生化第七届全国代表大会暨第十三次学术交流会 . 2014

7. 羊毛甾醇14-α去甲基酶（CYP51）基因调节小鼠卵母细胞减数分裂成熟和血浆胆固醇代谢研究 [A] . 王超 . 2006

1. 一种克隆植物减数分裂基因的方法和一种植物减数分裂基因的cDNA序列 [P] . 中国专利： CN1351168A . 2002-05-29

2. 一种快速鉴定水稻减数分裂基因基因型的方法及其特异性分子标记 [P] . 中国专利： CN113913545A . 2022-01-11

3. '' method for producing a saccharomyces cerevisiae strain with introduced genes encoding xylose reductase, xylitol dehydrogenase and xylulokinase and with enhanced ethanol production, enhanced xylose conversion and reduced axitol production, introduced saccharomyces cerevisiae strain encoding xylose reductase , with enhanced ethanol production, xylitol dehydrogenase and xylulokinase, enhanced xylose conversion and reduced xylitol production, enhanced ethanol producing saccharomyces cerevisiae strain, enhanced xylose conversion and reduced xylitol production, ethanol producing saccharomyces cerevisiae strain enhanced xylose conversion, reduced xylitol production, enhanced ethanol producing saccaromyces cerevisiae strain, enhanced xylose conversion, enhanced ethanol production, reduced xylitol production, and increased inhibitor tolerance and use of a '' strain [P] . 外国专利： BR112013011815A2 . 2017-10-31

机译：''生产具有引入的编码木糖还原酶，木糖醇脱氢酶和木酮糖酶基因的酿酒酵母菌株的方法，并具有增强的乙醇产量，增强的木糖转化率和减少的木糖醇产量，引入引入的编码木糖还原酶的酿酒酵母菌株，增强的乙醇产量，木糖醇脱氢酶和木酮糖激酶，提高的木糖转化率和降低的木糖醇产量，提高的乙醇生产酵母菌菌株，提高的木糖转化率和减少的木糖醇产量，乙醇生产的酿酒酵母菌株，增强的木糖转化率，降低的木糖醇产量，提高的乙醇生产酵母菌，提高的木糖酵母转化率，提高的木糖转化率，乙醇生产，木糖醇生产减少，抑制剂耐受性提高和使用''菌株

4. Scion of yeast Saccharomyces cerevisiae AM1-d, application of the scion of yeast Saccharomyces cerevisiae AM1-d for production of 2-phenylethyl alcohol and application of the substrate for producing of 2-phenylethyl alcohol by the scion of yeast Saccharomyces cerevisiae AM1-d, [P] . 外国专利： PL226680B1 . 2017-08-31

机译：酵母Saccharomyces AM1-d的接穗，酵母Saccharomyces AM1-d的接穗在酿酒酵母AM1-d的接穗中的应用，用于生产2-苯乙醇，以及用于生产2-苯基乙醇的底物，

5. Scion of yeast Saccharomyces cerevisiae AM1-d, application of the scion of yeast Saccharomyces cerevisiae AM1-d for production of 2-phenylethyl alcohol and application of the substrate for producing of 2-phenylethyl alcohol by the scion of yeast Saccharomyces cerevisiae AM1-d, [P] . 外国专利： PL408170A1 . 2015-11-23

机译：酵母Saccharomyces AM1-d的接穗，酵母Saccharomyces AM1-d的接穗在酿酒酵母AM1-d的接穗中的应用，用于生产2-苯乙醇，以及用于生产2-苯基乙醇的底物，

相关主题

Aym1, a mouse meiotic gene identified by virtue of its ability to activate early meiotic genes in the yeast Saccharomyces cerevisiae

摘要

著录项

相似文献

相关主题

期刊订阅