No “Kindlin,” it’s all about HSC balance

摘要

![Figure][1]/imgInsight from Paul FrenetteIntegrins are known to promote the quiescence of hematopoietic stem cells (HSCs), but the precise mechanism has been unclear. In this issue, [Ruppert et al.][2] use mice deficient in Kindlin-3 (K3), an intracellular protein that regulates