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首页> 外文期刊>The journal of thoracic and cardiovascular surgery >Proximal aortic surgery in the elderly population: Is advanced age a contraindication for surgery?
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Proximal aortic surgery in the elderly population: Is advanced age a contraindication for surgery?

机译:老年人近端主动脉手术:高龄手术的禁忌症吗?

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ObjectiveThe study objective was to describe the clinical outcomes of elderly patients undergoing ascending aortic surgery.MethodsPatients aged 70?years or older who underwent ascending aortic surgery between January 2002 and December 2013 were examined. Of 415 included patients, 285 were elderly patients (age 70-79?years) and 130 were very elderly (age ≥80?years). Logistic regression and Cox proportional hazards models were used to evaluate operative mortality and long-term survival, respectively.ResultsSurgical indications included aortic aneurysm (63.1%), calcified aorta with need for other cardiac procedure (26.4%), and type A dissection (10.5%). Compared with elderly patients, the very elderly patients had a higher burden of comorbidities and operative mortality (13% vs 7%, P?P?P??.05). Kaplan–Meier estimates of survival at 1 and 5?years were 85.6% and 72.6% for elderly patients versus 79.2% and 57.1% for the very elderly patients. Age was a strong risk variable for late mortality in the unadjusted and adjusted analyses.ConclusionsAfter adjusting for these comorbidities, the cause of aortic disease, and the type of procedure, age was not an independent predictor of operative mortality, but was strongly associated with reduced late survival. Thus, advanced age alone should not be an absolute contraindication for ascending aortic surgery.
机译:目的研究目的是描述接受升主动脉手术的老年患者的临床结果。方法对2002年1月至2013年12月期间接受升主动脉手术的70岁及以上患者进行检查。在415例患者中,285例是老年患者(年龄70-79岁),130例非常老病(年龄≥80岁)。结果分别采用Logistic回归和Cox比例风险模型评估手术死亡率和长期生存率。结果手术指征包括主动脉瘤(63.1%),需要其他心脏手术的钙化主动脉(26.4%)和A型解剖(10.5)。 %)。与老年患者相比,老年患者的合并症和手术死亡率更高(13%vs 7%,P

P <> 0.05)。 Kaplan–Meier估计老年患者1年和5年生存率分别为85.6%和72.6%,而老年患者则为79.2%和57.1%。在未经调整和调整的分析中,年龄是晚期死亡的重要风险变量。结论在对这些合并症,主动脉疾病的病因和手术类型进行调整后,年龄并不是手术死亡率的独立预测因素,但与降低手术死亡率密切相关晚期生存。因此,仅高龄不应是升主动脉手术的绝对禁忌症。

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