首页> 外文期刊>The Journal of Bone and Joint Surgery. British VolumecBritish Orthopaedic Association , Australian Orthopaedic Association , Canadian Orthopaedic Association . . . [et al] >A double-blind randomised controlled study comparing subacromial injection of tenoxicam or methylprednisolone in patients with subacromial impingement
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A double-blind randomised controlled study comparing subacromial injection of tenoxicam or methylprednisolone in patients with subacromial impingement

机译:一项双盲随机对照研究,比较了在肩峰以下撞击症患者的肩峰下注射替诺昔康或甲基强的松龙的情况

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We have carried out a prospective double-blind randomised controlled trial to compare the efficacy of a single subacromial injection of the non-steroidal anti-inflammatory drug, tenoxicam, with a single injection of methylprednisolone in patients with subacromial impingement. A total of 58 patients were randomly allocated into two groups. Group A received 40 mg of methylprednisolone and group B 20 mg of tenoxicam as a subacromial injection along with lignocaine. The Constant-Murley shoulder score was used as the primary outcome measure and the Disability of Arm, Shoulder and Hand (DASH) and the Oxford Shoulder Score (OSS) as secondary measures. Six weeks after injection the improvement in the Constant-Murley score was significantly greater in the methylprednisolone group (p = 0.003) than in the tenoxicam group. The improvement in the DASH score was greater in the steroid group and the difference was statistically significant and consistent two (p < 0.01), four (p < 0.01) and six weeks (p < 0.020) after the injection. The improvement in the OSS was consistently greater in the steroid group than in the tenoxicam group. Although the difference was statistically significant at two (p < 0.001) and four (p = 0.003) weeks after the injection, it was not at six weeks (p = 0.055). Subacromial injection of tenoxicam does not offer an equivalent outcome to subacromial injection of corticosteroid at six weeks. Corticosteroid is significantly better than tenoxicam for improving shoulder function in tendonitis of the rotator cuff after six weeks.
机译:我们进行了一项前瞻性双盲随机对照试验,以比较在非肩峰撞击症患者中,将非甾体类抗炎药替诺昔康一次肩峰以下注射与单次注射甲基强的松龙的疗效。共有58例患者随机分为两组。 A组接受40 mg甲基强的松龙,B组20 mg替诺昔康与亚诺卡因一起进行亚顶峰注射。将Constant-Murley肩膀评分用作主要结局指标,而手臂,肩膀和手部残疾(DASH)和牛津肩膀成绩(OSS)则作为次要指标。注射后六周,甲基泼尼松龙组的Constant-Murley评分改善幅度明显大于替诺昔康组(p = 0.003)。在类固醇组中,DASH评分的改善更大,并且差异具有统计学意义,并且在注射后的两个(p <0.01),四个(p <0.01)和六个星期(p <0.020)前后一致。甾体激素组的OSS改善持续优于替诺昔康组。尽管在注射后两周(p <0.001)和四周(p = 0.003),差异具有统计学意义,但在六周时(p = 0.055),差异并不明显。腹膜下注射替诺昔康不能在六周后提供与皮质类固醇的腹膜下注射等效的结果。六个星期后,皮质类固醇在改善肩袖肌腱炎的肩部功能方面明显优于替诺昔康。
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