A posteriori anisotropy study of ultra-high energy cosmic rays (UHECRs) with the Pierre Auger Observatory (PAO) has shown evidence of an excess of cosmic-ray particles above 55?EeV within 18° of the direction of the radio galaxy Centaurus A. However, the origin of the excess remains elusive. We simulate the propagation of different species of particles coming from the direction of Centaurus A in the Galactic magnetic fields and find that only particles of nuclear charge Z 10 can avoid being deflected outside of the 18° window of Centaurus A. On the other hand, considering the increasingly heavy composition of UHECRs at the highest energies measured by PAO, a plausible scenario for cosmic rays from the direction of Centaurus A can be found if they consist of intermediate-mass nuclei. The chemical composition of cosmic rays can be further constrained by lower-energy cosmic rays of the same rigidity. We find that cosmic-ray acceleration in the lobes of Centaurus A is not favored, while acceleration in the stellar winds that are rich in intermediate-mass nuclei could meet the requirement. This suggests that the observed excess may originate from cosmic-ray accelerators induced by stellar explosions in the star-forming regions of Centaurus A and/or the Centaurus cluster located behind Centaurus A.
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