Recent ground-based mid-infrared spectra of 29 late-type stars, most with substantial dust shells, are compared to ground-based spectra of these stars from the 1960s and 1970s and to IRAS-LRS spectra obtained in 1983. The spectra of about half the stars show no detectable changes, implying that their distributions of circumstellar material and associated dust grain properties have changed little over this time interval. However, many of the stars with strong silicate features showed marked changes. In nearly all cases the silicate peak has strengthened with respect to the underlying continuum, although there is one case (VY CMa) in which the silicate feature has almost completely disappeared. This suggests that, in general, an oxygen-rich star experiences long periods of gradual silicate feature strengthening, punctuated by relatively rare periods when the feature weakens. We discuss various mechanisms for producing the changes, favoring the slow evolution of the intrinsic dust properties (i.e., the chemical composition or grain structure). Although most IRAS spectra agree well with ground-based spectra, there are a number of cases in which they fall well outside the expected range of uncertainty. In almost all such cases, the slopes of the red and blue LRS spectra do not match in their region of overlap.
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