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Hepatic Steatosis-a complex interaction of germs, genes and grub.

机译:肝脂肪变性-细菌,基因和幼虫的复杂相互作用。

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摘要

Non-alcoholic fatty liver disease (NAFLD) has a prevalence of 7–10% among children in the developed world, making it the most common cause of chronic liver disease in this population. Its prevalence is rising concomitant with the rise in obesity.1 NAFLD incorporates a spectrum of liver abnormalities, ranging from simple steatosis, to, non-alcoholic steatohepatitis (NASH), involving various degrees of inflammation, ballooning and fibrosis. NASH may evolve into cirrhosis, accounting for its place as the second most common listing indication for adult liver transplantation (LT) in the United States.1 It is vital to intervene in the paediatric population to avert this outcome.
机译:在发达国家儿童中,非酒精性脂肪肝疾病(NAFLD)的患病率为7-10%,使其成为该人群中慢性肝病的最常见原因。它的患病率随着肥胖的增加而上升。1NAFLD包括一系列肝脏异常,从单纯性脂肪变性到非酒精性脂肪性肝炎(NASH),涉及不同程度的炎症,气球和纤维化。 NASH可能发展为肝硬化,在美国成人肝移植(LT)中列为第二常见的适应症。1干预儿科人群以防止这种结果至关重要。

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