Objective: The objective of this paper is to describe the epidemiological and clinical characteristics of Kawasaki disease(KD) in Guangdong Province, China during 5 year-period from January 1995 to December 1999.Methods: A province-wide epidemiological survey on Kawasaki disease was made by the Sino-Japan Kawasaki Disease Study Group. The questionnaire form and the diagnostic criteria of KD were sent to the departments of pediatrics of all the hospitals of county level. All the patients diagnosed in 1995 to 1999 were required to be reported. Results: A total of 111(71.2%) hospitals responded and 537 cases of KD were confirmed. The incidence rate was 5.93 per 100,000 children < 5 Yrs. old in Guangdong province. Of total patients reported, 51.8% were younger than 2 years old and 75.6% were younger than 4 years old with male to female ratio of 2.23:1. The number of patients was higher during April to June every year and lower during October to December. Areas of the highest incidence rate were found in Shenzhen and Zhuhai and next were Guangzhou and pearl river delta, the incidence rate in the North Guangdong was the lowest. The proportion of patients with cardiac sequelae was 75 cases (14%). There were 1 fatal case with a fatality rate of 0.2%.Conclusions: The incidence rate of KD in Guangdong was higher than that in Jiangsu and Shanxi and obviously lower than that in Japan. As similar to Japan, Jiangsu and Shanxi in epidemiologic patterns and distribution feature. Areas of the highest incidence rate were found in good economic status and the incidence rate in difficult economic status was lower.
展开▼
