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外文期刊>Pediatric Research
>177 SIMPLE AND CHEAP APPARATUS FOR INHALATORY APPLICATION OF NITRIC OXIDE (NO) WITH THE POSSIBILITY OF CONTINUOUS MONITORING NO AND NO2 IN THE INHALATION MIXTURE
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177 SIMPLE AND CHEAP APPARATUS FOR INHALATORY APPLICATION OF NITRIC OXIDE (NO) WITH THE POSSIBILITY OF CONTINUOUS MONITORING NO AND NO2 IN THE INHALATION MIXTURE
Introduction The direct application of NO into the ventilator's circuit has disadvantages: 1) it is expensive; 2) large volume of this inert gas carrying NO can decrease FiO2 in the respiratory circuit of the ventilator.Methods NO is diluted with nitrogen (up to 300ml/min) in the first stage. A part (0-300 ml/min) is then sucked off from this mixture and this denned amount is substituted with oxygen. Quartz capillary is the source of stabilized low-volume flow of NO. Its outer surface is covered with polyamide, which secures its elasticity. The NO concentrations are monitored using a simple chemiluminescence analyser. NO2 is analysed by a aerosol chemiluminescence detector.Results The Quartz capillary is sufficiently accurate (for five months it secured the NO flow of 1,8 +/- 0,05 ml/min). The stability for dosing 17 ppm was +/- 8%, for 41 ppm +/- 6%. The chemiluminescence aerosol detector of NO2 detects continuously the concentrations even in the units ppt.Conclusions This apparatus presents a simple, sufficiently accurate, and particularly cheap method of the NO application and monitoring NO, NO2 concentrations within the ventilator's respiratory circuit.
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