Mean arterial and venous CBFV (cm/sec) were measured simultaneously by Doppler Velocimetry of the Antetion Cerebral Artery and Internal Cerebral Vein in 3 groups of newborn infants of various Gestational Ages (GA, w), Birth Weights(BW,g) and Post-Natal Ages (PNA,d) Group 1, 53 normal infants, GA 26-41 w, BW 950-3890 g, PNA 1-60d: Group 2, 27 infants with RDS treated with different levels of CPAP, GA 26-34w, BW 830-3130g, PNA 1-30d: Group 3, 18 infants with IPIE, GA 32-42w, BW 1180-3750g, PNA 1-3d, diagnosis of IPIE was based on the following criteria: need for vigorous resuscitation at birth; severe acidosis (BD 12 and pH 720) within one hour of age: clinical evidence of Grade 2 in 3 IPIE by Same classification (*)In infants of Group 1, mean arterial and venous CBFV were GA and PNA dependent, To they measured significantly (p2O CPAP movement In infants of Group 3, mean arterial and venous CBFV were considered “abnormal” when higher or lower than 2 SO from the average noraml values obtained in infants of Group 1 By these criteria, 6 infants with both “abnormal” arterial and venous CBFV all had a severe outcome, ie 4 died and 2 land severe neurological abnormalities at follow-up; bone of the 12 infants with both “normal” (7)or just one “normal” (5) CBFV either died of became severely handicapped The present study providers normal reterence values of arterial and venous CBFV in the newborns of suggests that monitoring of mean venous CBFV in infants with RDS could provide useful information on the possible interference of excessive CPAP on the cerebral circulation: finally, it suggests that the simultaneous evaluation of both arterial and venous CBFV is a better medication of severe outcome in infants with IPIE than the measurement of arterial CBFV alone (*)Samat H B and Samat N S Arch Neurol 1976:33 696-705
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机译：通过多普勒测速仪同时测量了3个不同胎龄（GA，w），出生体重（BW，g）和出生后的新生婴儿的平均动脉和静脉CBFV（cm / sec） -Natal Ages（PNA，d）第1组，53名正常婴儿，GA 26-41 w，BW 950-3890 g，PNA 1-60d：第2组，27名具有不同水平CPAP治疗的RDS婴儿，GA 26-34w ，BW 830-3130g，PNA 1-30d：第3组，18例IPIE婴儿，GA 32-42w，BW 1180-3750g，PNA 1-3d，IPIE的诊断基于以下标准：出生时需要剧烈复苏;一小时内出现严重酸中毒（BD 12和pH 720）：3种IPIE分级为2级的临床证据（*）在第1组婴儿中，平均动脉和静脉CBFV依赖于GA和PNA，对其进行了显着测量（p2O CPAP运动在第3组婴儿中，平均动脉和静脉CBFV当高于或低于第1组婴儿获得的平均Noraml值的2 SO时，被视为“异常”。根据这些标准，有6名婴儿均具有“异常”动脉且静脉CBFV均具有严重的预后，即在随访时4例死亡和2例严重神经系统异常;“正常”（7）或仅一个“正常”（5）的12例婴儿的骨骼死亡严重残障本研究提供了新生儿的动脉和静脉CBFV的正常抵抗力值，表明监测RDS婴儿的平均静脉CBFV可以提供有关过度CPAP对脑循环可能干扰的有用信息：最后，它提示与单独测量动脉CBFV相比，同时评估动脉和静脉CBFV是IPIE婴儿严重后果的更好药物（*）Samat H B和Samat N S Arch Neurol 1976：33 696-705
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