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>Development of a PrGO-Modified Electrode for Uric Acid Determination in the Presence of Ascorbic Acid by an Electrochemical Technique
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Development of a PrGO-Modified Electrode for Uric Acid Determination in the Presence of Ascorbic Acid by an Electrochemical Technique
An attractive electrochemical sensor of poly(3,4-ethylenedioxythiophene)/reduced graphene oxide electrode (PrGO) was developed for an electrochemical technique for uric acid (UA) detection in the presence of ascorbic acid (AA). PrGO composite film showed an improved electrocatalytic activity towards UA oxidation in pH 6.0 (0.1 M PBS). The PrGO composite exhibited a high current signal and low charge transfer resistance ( R ct ) compared to a reduced graphene oxide (rGO) electrode or a bare glassy carbon electrode (GCE). The limit of detection and sensitivity of PrGO for the detection of UA are 0.19 μM (S/N = 3) and 0.01 μA/μM, respectively, in the range of 1–300 μM of UA.
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机译:聚(3,4-乙撑二氧噻吩)/还原氧化石墨烯电极(PrGO)的一种有吸引力的电化学传感器被开发用于在抗坏血酸(AA)存在下检测尿酸(UA)的电化学技术。 PrGO复合膜在pH 6.0(0.1 M PBS)下对UA氧化表现出改善的电催化活性。与还原的氧化石墨烯(rGO)电极或裸玻璃碳电极(GCE)相比,PrGO复合材料显示出高电流信号和低电荷转移电阻(R ct)。在UA的1–300μM范围内,用于检测UA的PrGO的检出限和灵敏度分别为0.19μM(S / N = 3)和0.01μA/μM。
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