SMALL FOR GESTATIONAL AGE (SGA) INFANTS: PLASMA MINERALOCORTICOIDS, GLUCOCORTICOIDS AND PR0GESTINS AT BIRTH AND DURING THE NEONATAL PERIOD

摘要

The small adrenal cortex of SGA infants may play a role in the pathogenesis of their frequent postnatal problems. We therefore evaluated adrenocortical function of SGA infants at birth and during postnatal adaptation. In 22 vaginally delivered term infants (SGA * SGA vs AGA p < 0.05).Conclusions: Obviously, SGA infants are maintaining high Aldo levels throughout the first week of life which points to an increased activity of the Renin-Angiotensin-Aldo-Axis. In contrast, the low levels of active (B,F) and inactive (S,E) glucocorticoids at 2 h and 12 h may reflect a reduced response to the stress of birth in SGA infants.# Blood samples taken of routine blood sampling.