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Patterns of Inhaled Antiinflammatory Medication Use in Young Underserved Children With Asthma

机译:吸入性抗炎药的使用模式在未得到充分服务的哮喘小儿童中

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BACKGROUND. Asthma guidelines advocate inhaled corticosteroids as the cornerstone treatment of persistent asthma, yet several studies report underuse of inhaled corticosteroids in children with persistent asthma. Moreover, few studies use objective pharmacy data as a measure of drug availability of asthma medications. We examined factors associated with the use of inhaled corticosteroids in young underserved children with persistent asthma using pharmacy records as their source of asthma medications.METHODS. This was a cross-sectional analysis of questionnaire and pharmacy record data over a 12-month period from participants enrolled in a randomized clinical trial of a nebulizer educational intervention.RESULTS. Although exposure to ≥1 inhaled corticosteroids refill was high at 72%, 1 of 5 children with persistent asthma had either no medication or only short-acting β agonist fills for 12 months. Only 20% of children obtained ≥6 inhaled corticosteroids fills over 12 months. Obtaining ≥3 inhaled corticosteroids fills over 12 months was significantly associated with an increase in short-acting β agonist fills and receiving specialty care in the regression models while controlling for child age, asthma severity, number of emergency department visits, having an asthma action plan, and seeking preventive care for the child's asthma.CONCLUSIONS. Overreliance on short-acting β agonist and underuse of inhaled corticosteroid medications was common in this group of young children with persistent asthma. Only one fifth of children obtained sufficient controller medication fills.
机译:背景。哮喘指南主张将吸入糖皮质激素作为持续性哮喘的基石,但一些研究报告说,对于患有持续性哮喘的儿童,吸入糖皮质激素的使用不足。此外,很少有研究使用客观药房数据来衡量哮喘药物的药物利用率。我们使用药房记录作为哮喘药物的来源,研究了在患有哮喘,服务不足的持续性哮喘小儿使用吸入糖皮质激素的相关因素。这是对参加雾化器教育干预随机临床试验的参与者在12个月内的问卷和药房记录数据进行的横断面分析。结果。尽管暴露于≥1吸入皮质类固醇补充剂的比例高达72%,但5名持续性哮喘患儿中有1名在12个月内没有药物治疗或仅使用了短效β激动剂。在12个月内,仅20%的儿童获得了≥6的吸入糖皮质激素。在12个月内获得≥3的吸入糖皮质激素填充物与短效β受体激动剂填充物增加以及在回归模型中接受专科护理(同时控制儿童年龄,哮喘严重程度,急诊就诊次数,制定哮喘行动计划)显着相关,并寻求对儿童哮喘的预防护理。在这种患有持续性哮喘的幼儿中,过度依赖短效β激动剂和吸入皮质类固醇药物使用不足是常见的。只有五分之一的儿童获得了足够的补充控制药物。

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