首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >To Dye or Not to Dye: A Randomized, Clinical Trial of a Triple Dye/Alcohol Regime Versus Dry Cord Care
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To Dye or Not to Dye: A Randomized, Clinical Trial of a Triple Dye/Alcohol Regime Versus Dry Cord Care

机译:染或不染:三重染料/酒精体系与干线护理的随机临床试验

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Objective. The use of antibacterial agents to clean and dry the stump of the newborn’s umbilical cord after birth has recently been abandoned by many neonatal units in favor of dry cord care. The objective of this study was to compare cord bacterial colonization and morbidity among newborns whose cords were treated with triple dye and alcohol versus dry cord care.Methodology. We randomly allocated 766 newborns to either 2 applications of triple dye to the umbilical cord stump on the day of birth with alcohol swabbing twice daily until the cord fell off ( n = 384) or dry care ( n = 382). Dry care consisted of spot cleaning soiled skin in the periumbilical area with soap and water, wiping it with a dry cotton swab or cloth, and allowing the area to air dry. Umbilical stumps on all subjects were swabbed and cultured. Community health nurses visiting at 2 or 3 days after hospital discharge observed the stump for signs of infection. Follow-up phone calls were made to mothers within 3 weeks of discharge.Results. One infant in the dry care group was diagnosed with omphalitis. The umbilical stump was colonized with α-hemolytic streptococcus and coagulase-negative staphylococcus. Infants in the dry care group were significantly more likely to be colonized with Escherichia coli (34.2% vs 22.1%), coagulase-negative staphylococci (69.5% vs 50.5%), Staphylococcus aureus (31.3% vs 2.8%), and group B streptococci (11.7% vs 6.0%). Community health nurses were significantly more likely to observe exudate (7.4% vs 0.3%) and foul odor (2.9% vs 0.7%) among infants allocated to the dry care group during the home visit.Conclusions. Omphalitis remains a clinical issue. Cessation of bacteriocidal care of the umbilical stump must be accompanied by vigilant attention to the signs and symptoms of omphalitis.
机译:目的。最近,许多新生儿单位放弃了使用抗菌剂来清洁和干燥新生儿脐带的残端,而倾向于干脐带护理。这项研究的目的是比较用三重染料和酒精治疗脐带与干脐带护理的新生儿脐带细菌定植和发病率。我们在出生当天随机将766名新生儿随机分配给脐带残端2种三联染料,每天两次用酒精擦拭直至脐带脱落(n = 384)或干洗(n = 382)。干燥护理包括用肥皂和水点洗眼周区域的脏污皮肤,然后用干燥的棉签或布擦拭,然后使该区域风干。擦拭并培养所有受试者的脐带残端。出院后2或3天就诊的社区卫生护士观察了残端是否有感染迹象。分娩后3周内给母亲进行了跟进电话。干燥护理组中的一名婴儿被诊断出患有眼炎。脐部残端定植有α-溶血性链球菌和凝固酶阴性葡萄球菌。干燥护理组的婴儿更可能被大肠杆菌(34.2%vs 22.1%),凝固酶阴性葡萄球菌(69.5%vs 50.5%),金黄色葡萄球菌(31.3%vs 2.8%)和B组链球菌定植。 (11.7%对6.0%)。在家庭护理期间,分配给干洗护理组的婴儿中,社区卫生护士更有可能观察到渗出液(7.4%vs. 0.3%)和恶臭(2.9%vs 0.7%)。眼炎仍然是临床问题。停止对脐带残端进行杀菌处理时,必须格外注意脐带炎的体征和症状。

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