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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Effects of Methylphenidate on Hyperactive Children's Ability to Sustain Attention
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Effects of Methylphenidate on Hyperactive Children's Ability to Sustain Attention

机译:哌醋甲酯对多动症儿童维持注意力能力的影响

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摘要

The purposes of this study were to investigate the attentional characteristics of hyperactive children, the relationship of subjective and objective measures of these characteristics, and the effects of methylphenidate on these measures of attention. Forty-five hyperactive children, ages 6 to 10 years, were entered into an 18-week study of the effects of methylphenidate (Ritalin) on attention. Measures included rating scales completed by teachers and parents and a vigilance task. All measures reflected significant changes during the period of investigation. Attention and behavior were significantly improved under drug conditions and significantly worsened when methylphenidate was discontinued. However, only performance on the objective measure returned to predrug levels; final off-drug parent and teacher ratings remained improved over initial reports. Parent ratings of behavior, and specifically of children's ability to attend, were unrelated to equivalent teacher ratings. Teachers' ratings of attention correlated significantly with performance on the vigilance task, discriminated between on-drug and off-drug conditions, and discriminated between children who obtained normal or near normal predrug scores on the objective measure and those who performed poorly on this measure. Methylphenidate improved attentional performance for children who had poor predrug scores on the vigilance task, but did not produce a statistically significant change on the scores of children with normal predrug performance.
机译:这项研究的目的是调查多动儿童的注意力特征,这些特征的主观和客观测量之间的关系以及哌醋甲酯对这些注意量的影响。年龄为6至10岁的45名多动症儿童参加了为期18周的研究,研究了哌醋甲酯(利他林)对注意力的影响。措施包括由教师和家长完成的评分量表和警戒任务。所有措施均反映了调查期间的重大变化。在药物条件下,注意力和行为得到了显着改善,而哌醋甲酯停药后,注意力和行为明显恶化。但是,只有在客观测量方面的表现才恢复到药物前水平;与最初的报告相比,最终的禁毒父母和老师的评分仍然有所提高。父母的行为评分,尤其是孩子的上课能力,与同等的教师评分无关。教师的注意等级与警惕任务的执行情况显着相关,可以区分药物使用情况和药物使用情况,也可以区分在客观测量中获得正常或接近正常的药物前成绩的孩子与在此测量中表现不佳的孩子。对于在警戒任务中前药得分低的孩子,哌醋甲酯改善了注意力表现,但对前药性能正常的孩子的得分没有统计学上的显着变化。

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