首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >PERSISTENCE OF IMMUNITY FOLLOWING MONOVALENT AND COMBINED LIVE MEASLES, MUMPS, AND RUBELLA VIRUS VACCINES
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PERSISTENCE OF IMMUNITY FOLLOWING MONOVALENT AND COMBINED LIVE MEASLES, MUMPS, AND RUBELLA VIRUS VACCINES

机译:新型和混合活检,腮腺炎和RUBELLA病毒疫苗后免疫力的持久性

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Neutralizing antibody following Jeryl Lynn mumps virus vaccine persisted for at least six years after vaccination without substantial decline in titer, and protective immunity was solidly retained through the sixth observation year. Hemagglutination-inhibiting antibodies following vaccination with Enders' original Edmonston and more attenuated Moraten and Schwarz lines measles vaccines were retained in comparable level through the fourth year.Antibody following HPV-77 duck rubella vaccine was retained without important decline for at least 3? years. The pattern for antibody persistence following combined measles-mumps-rubella and mumps-rubella vaccine measured at three years and for measles-rubella vaccine measured at two years was the same as for the monovalent vaccines indicating no alteration in the retention of immunity. None of the children in this study lost his antibody completely. Subclinical reinfection evidenced by antibody increase was commonly seen in vaccinated persons.
机译:疫苗接种后,杰里尔·林恩腮腺炎病毒疫苗接种后的中和抗体至少持续了6年,滴度没有明显下降,并且在第六个观察年中仍牢固地保留了保护性免疫力。到Enders最初的Edmonston疫苗和减毒的Moraten和Schwarz品系麻疹疫苗接种后的血凝抑制抗体在第四年中保持可比较的水平。HPV-77鸭风疹疫苗后的抗体保留了至少3倍,没有明显下降。年份。三年后测量的麻疹-腮腺炎-风疹和腮腺炎-风疹联合疫苗和两年后测量的麻疹-风疹疫苗联合后的抗体持久性模式与单价疫苗相同,表明免疫力保持不变。在这项研究中,没有一个孩子完全失去他的抗体。在抗体接种者中通常可见由抗体增加所证明的亚临床再感染。

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