Pharmacological Investigation of Tragia plukenetii R. Smith Leaf Extracts for Anti Convulsant Activity by Using Maximal Electroshock Induced Convulsions in Swiss Albino Mice.

摘要

ABSTRACT The aim of this study was to assess the anticonvulsant activity of Tragia plukenetii R Smith leaf extracts against maximal electroshock seizures (MES) in mice. 20 swiss albino mice were selected and divided into five groups of four mice. The treatment groups were Group 1: Control group (0.9% normal saline, 5ml/ kg, i.p); Group-2: Standard group (phenytoin at a dose of 25 mg/kg, i.p); Group 3: Benzene leaf extract (TPBE100mg/kg i.p); Group 4: Chloroform leaf extract (TPCE-100mg/kg i.p);.